Case Studies : Renal tubular acidosispresenting as osteomalacia. Refractory rickets caused by mild distal renal tubular acidosis. A case of severe osteomalacia caused by Tubulointerstitial nephritis with Fanconi syndrome in asymptomatic primary billiary cirrhosis.
TYPE 1 RTA MANUAL
Harison’s Manual Of Medicine, 18th Edition. Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J.Keywords: Osteomalacia Renal Tubular Acidosis Hypokalemia Hypophosphatemia
![type 1 rta type 1 rta](https://image2.slideserve.com/4769269/to-summarise-type-1-rta-l.jpg)
She was diagnosed with osteomalacia induced by distal type RTA due to the loss of calcium salts from bone and hypophosphatemia. She was complaining with low back pain due to fracture on left medial side of inferior pubic ramus and endplate fracture on right side superior L4 and BMD examination showed low mineral density. Hereby we report a case of 22 years old Asian woman who wasįirstly diagnosed with distal type RTA several years ago then started developing bone involvement recently. However, distal RTA or type 1 can also cause osteomalacia.
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Among all type of RTA, proximal RTA or type 2 is known have association with Fanconi syndrome and bone involvement. RTA is classified into 3 major forms, such as proximal RTA or type 2 distal RTA or type 1 and hyperkalemic RTA or type 4. Renal Tubular Acidosis, a group of disorders characterized by defective renal acid-base regulation, can impair mineralization of bone matrix in adults known as osteomalacia.